• Development of Atlantic Salmon (Salmo salar L.) Under Hypoxic Conditions Induced Sustained Changes in Expression of Immune Genes and Reduced Resistance to Moritella viscosa 

      Krasnov, Aleksei; Burgerhout, Erik; Johnsen, Hanne; Tveiten, Helge; Bakke, Anne Flore; Lund, Hege; Afanasyev, Sergey; Rebl, Alexander; Johansen, Lill-Heidi (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-02)
      Atlantic salmon is characterized with high sensitivity to low dissolved oxygen (DO) levels. Hypoxia can affect diverse biological processes with consequences that can be manifested immediately or with delay. Effects of hypoxia on the immune system and the resistance to a bacterial pathogen were investigated. Two groups were reared at, respectively, normal (NO, 80–100%) and low (LO, 60%) levels of ...
    • Impacts of Early Life Stress on the Methylome and Transcriptome of Atlantic Salmon 

      Moghadam, Hooman; Johnsen, Hanne; Robinson, Nick; Andersen, Øivind; Jørgensen, Even Hjalmar; Johnsen, Helge K.; Bæhr, Vegar J.; Tveiten, Helge (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-10)
      Exposure to environmental stressors during early-life stages can change the rate and timing of various developmental processes. Epigenetic marks affecting transcriptional regulation can be altered by such environmental stimuli. To assess how stress might affect the methylome and transcriptome in salmon, fish were treated using cold-shock and air-exposure from the eye-stage until start-feeding. ...
    • Key genes and regulators associated with sexual differentiation and gonad development in Atlantic cod (Gadus morhua L.) 

      Johnsen, Hanne (Doctoral thesis; Doktorgradsavhandling, 2012-02-17)
      Atlantic cod (Gadus morhua L.) is a promising cold-water aquaculture species, but early sexual maturation is a major problem in today’s cod farming. Teleosts display a wide variety of sex determination and sex differentiation mechanisms, ranging from genetic to environmental factors and the sexual plasticity in gonads and brain possibly reflects on a combination of these. From a practical point of ...
    • Production of sterile Atlantic salmon by germ cell ablation with antisense oligonucleotides 

      Tveiten, Helge; Andersen, Øivind; Swain, Jaya Kumari; Johnsen, Hanne; Mommens, Maren; Slanchev, Krasimir (Journal article; Tidsskriftartikkel, 2023)
      Cultivation of sterile-only fish in aquaculture offers multiple benefits of environmental, economical, and social value. A reliable method for efficient sterilization without affecting fish welfare and performance traits would have significant impact on fish production practices. Here, we demonstrate sterilization of Atlantic salmon embryos by targeting the dead end gene with antisense oligonucleotides. ...